We are currently focused in the following main areas:
1. New dyes with improved photophysics, brighter, more photostable
2. Fighting pathogens: metabolite-sensing RNA-mediared gene-regulation processes
3. New fluorescent labeling strategies and ortoghonal chemistries for single-molecule FRET studies
4. Molecular machines involved in DNA and RNA processing
5. Single-molecule studies of conjugated light-emitting polymers
6. Single-molecule characterization of ubiquitin and sumo-related pathways
7. Mechanosensitive proteins
The two schemes below show the main biology areas in which we are currently working and the main single-molecule biophysical tools available in our labs in the School of Physics and the Shool of Biology:
