Prof David Harrison

Professor

Researcher profile

Phone

+44 (0)1334 46 4826

Email

djh20@st-andrews.ac.uk

PhD supervision

• Hazem Abdullah
• Minyeoung Kweon
• Anna Carberry
• Ennio Pecaver
• Clare Orange
• Greice Zickuhr
• Ngoc Anh Thu Trinh
• Craig Myles
• Myriam Kabu

Selected publications

• Open access

  Kinetic and thermodynamic characterization of human 4-oxo-L-proline reductase catalysis

  Pecaver, E., Zickuhr, G. M., Machado, T. F. G., Harrison, D. J. & da Silva, R. G., 18 Feb 2025, In: Biochemistry. 64, 4, p. 860-870 11 p.

  Research output: Contribution to journal › Article › peer-review

• Open access

  A phase I open-label, dose-escalation study of NUC-3373, a targeted thymidylate synthase inhibitor, in patients with advanced cancer (NuTide:301)

  Spiliopoulou, P., Kazmi, F., Aroldi, F., Holmes, T., Thompson, D., Griffiths, L., Qi, C., Parkes, M., Lord, S., Veal, G. J., Harrison, D. J., Coyle, V. M., Graham, J., Jeffry Evans, T. R. & Blagden, S. P., 2 Apr 2024, In: Journal of Experimental & Clinical Cancer Research. 43, 16 p.

  Research output: Contribution to journal › Article › peer-review

• Open access

  Adapting the design of the ongoing RAMPART trial in response to external evidence: an example for trials which take many years to run and report

  Meade, A., Frangou, E., Choodari-Oskooei, B., Larkin, J., Powles, T., Stewart, G. D., Albiges, L., Bex, A., Choueiri, T. K., Davis, I. D., Eisen, T., Fielding, A., Gedye, C., Harrison, D. J., Kaplan, R., Mulhere, S., Nathan, P., Patel, G., Patel, J. & Plant, H. & 9 others, Ritchie, A., Rush, H., Shakeshaft, C., Stockler, M. R., Suarez, C., Thompson, J., Thorogood, N., Venugopal, B. & Parmar, M. K. B., 1 Dec 2024, In: Contemporary Clinical Trials Communications. 42, 5 p., 101381.

  Research output: Contribution to journal › Article › peer-review

• Open access

  Adapting the design of the ongoing RAMPART trial in response to external evidence: An example for trials which take many years to run and report

  Meade, A., Frangou, E., Choodari-Oskooei, B., Larkin, J., Powles, T., Stewart, G. D., Albiges, L., Bex, A., Choueiri, T. K., Davis, I. D., Eisen, T., Fielding, A., Gedye, C., Harrison, D. J., Kaplan, R., Mulhere, S., Nathan, P., Patel, G., Patel, J. & Plant, H. & 9 others, Ritchie, A., Rush, H., Shakeshaft, C., Stockler, M. R., Suarez, C., Thompson, J., Thorogood, N., Venugopal, B. & Parmar, M. K. B., Dec 2024, In: Contemporary Clinical Trials Communications. 42, 101381.

  Research output: Contribution to journal › Article › peer-review

• Open access

  Automated reporting of cervical biopsies using artificial intelligence

  Mohammadi, M., Fell, C., Morrison, D., Syed, S., Konanahalli, P., Bell, S., Bryson, G., Arandjelović, O., Harrison, D. J. & Harris-Birtill, D., 22 Apr 2024, In: PLOS Digital Health. 3, 4, e0000381.

  Research output: Contribution to journal › Article › peer-review

• Open access

  DESI-MSI-guided exploration of metabolic-phenotypic relationships reveals a correlation between PI 38:3 and proliferating cells in clear cell renal cell carcinoma via single-section co-registration of multimodal imaging

  Zickuhr, G. M., Um, I. H., Laird, A., Harrison, D. J. & Dickson, A., Jul 2024, In: Analytical and Bioanalytical Chemistry. 416, 18, p. 4015–4028 14 p.

  Research output: Contribution to journal › Article › peer-review

• Open access

  Defining the mode of action of cisplatin combined with NUC-1031, a phosphoramidate modification of gemcitabine

  Patel, D., Dickson, A., Zickuhr, G. M., Um, I. H., Read, O. J., Melo Czekster, C., Mullen, P., Harrison, D. J. & Bre, J. L., 1 Dec 2024, In: Translational Oncology. 50, 11 p., 102114.

  Research output: Contribution to journal › Article › peer-review

• Open access

  Human 2'-deoxynucleoside 5'-phosphate N-hydrolase 1: the catalytic roles of Tyr24 and Asp80

  Carberry, A. E., Devi, S., Harrison, D. J. & da Silva, R. G., 2 Apr 2024, In: ChemBioChem. 25, 7, 10 p., e202400047.

  Research output: Contribution to journal › Article › peer-review

• Open access

  Kisspeptin is elevated in the brain after intracerebral haemorrhagic stroke

  Maheshwari, S., Um, I. H., Donachie, S., Asghar, N., McDade, K., Millar, T., Harrison, D. J. & Tello, J. A., 30 Dec 2024, In: Scientific Reports. 14, 11 p., 32046.

  Research output: Contribution to journal › Article › peer-review

• Open access

  Leveraging foundation models for enhanced detection of colorectal cancer biomarkers in small datasets

  Myles, C., Um, I. H., Harrison, D. J. & Harris-Birtill, D. C. C., 24 Jul 2024, Medical image understanding and analysis: 28th annual conference, MIUA 2024, Manchester, UK, July 24–26, 2024, proceedings, part I. Yap, M. H., Kendrick, C., Behera, A., Cootes, T. & Zwiggelaar, R. (eds.). Cham: Springer, p. 329-343 (Lecture notes in computer science; vol. 14859).

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

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