Dr Phillip Lowe

EPSRC Research Fellow

Researcher profile

Phone

+44 (0)1334 46 7254

Email

pl49@st-andrews.ac.uk

 

Selected publications

• Open access

  Exploring fluorinase substrate tolerance at C-2 of SAM

  Lowe, P. T., Lüddecke, I. T. & O'Hagan, D., 17 Nov 2024, In: ChemBioChem. 7 p., e202400861.

  Research output: Contribution to journal › Article › peer-review

• Open access

  Halogenated adenine and adenosine natural products in Streptomyces sp. JCM9888

  Chen, Y., Lowe, P., Deng, H. & O'Hagan, D., 30 Oct 2024, (E-pub ahead of print) In: European Journal of Organic Chemistry. Early View, 9 p., e202400578.

  Research output: Contribution to journal › Article › peer-review

• Open access

  4′-Fluoro-nucleosides and nucleotides: from nucleocidin to an emerging class of therapeutics

  Lowe, P. T. & O’Hagan, D., 7 Jan 2023, In: Chemical Society Reviews. 52, 1, p. 248-276 29 p.

  Research output: Contribution to journal › Review article › peer-review

• Open access

  Oligomerization engineering of the fluorinase enzyme leads to an active trimer that supports synthesis of fluorometabolites in vitro

  Kittilä, T., Calero, P., Fredslund, F., Lowe, P. T., Tezé, D., Nieto-Domínguez, M., O’Hagan, D., Nikel, P. I. & Welner, D. H., 27 Jan 2022, (E-pub ahead of print) In: Microbial Biotechnology. Early View, 11 p.

  Research output: Contribution to journal › Article › peer-review

• Open access

  A fluoride-responsive genetic circuit enables in vivo biofluorination in engineered Pseudomonas putida

  Calero, P., Volke, D. C., Lowe, P., Gotfredsen, C. H., O'Hagan, D. & Nikel, P. I., 7 Oct 2020, In: Nature Communications. 11, 11 p., 5045.

  Research output: Contribution to journal › Article › peer-review

• Open access

  An engineered E. coli strain for direct in vivo fluorination

  Markakis, K., Lowe, P. T., Davison-Gates, L., O'Hagan, D., Rosser, S. J. & Elfick, A., 3 Mar 2020, (E-pub ahead of print) In: ChemBioChem. Early View

  Research output: Contribution to journal › Article › peer-review

• A role for fluorine in flavours, fragrances and pheromones?

  Lowe, P. T. & O'Hagan, D., 15 Nov 2019, (E-pub ahead of print) In: Journal of Fluorine Chemistry. In press

  Research output: Contribution to journal › Article › peer-review

• Open access

  An enzymatic Finkelstein reaction: fluorinase catalyses direct halogen exchange

  Lowe, P. T., Cobb, S. L. & O'Hagan, D., 28 Aug 2019, In: Organic & Biomolecular Chemistry. 17, 32, p. 7493-7496 4 p.

  Research output: Contribution to journal › Article › peer-review

• Enzymatic radiosynthesis of a ¹⁸F-Glu-Ureido-Lys ligand for the prostate-specific membrane antigen (PSMA)

  Lowe, P. T., Dall'Angelo, S., Fleming, I. N., Piras, M., Zanda, M. & O'Hagan, D., 14 Feb 2019, In: Organic & Biomolecular Chemistry. 17, 6, p. 1480-1486 7 p.

  Research output: Contribution to journal › Article › peer-review

• Open access

  Two 3′-O-β-glucosylated nucleoside fluorometabolites related to nucleocidin in Streptomyces calvus

  Feng, X., Bello, D., Lowe, P. T., Clark, J. & O'Hagan, D., 7 Nov 2019, In: Chemical Science. 10, 41, p. 9501-9505 5 p.

  Research output: Contribution to journal › Article › peer-review

 

See more publications