Dr Shirley Graham

Research Fellow

Researcher profile

Phone

+44 (0)1334 46 2373

Email

sg71@st-andrews.ac.uk

Selected publications

• Open access

  Activation of Csm6 ribonuclease by cyclic nucleotide binding: in an emergency, twist to open

  McQuarrie, S., Athukoralage, J. S., McMahon, S. A., Graham, S., Ackermann, K., Bode, B. E., White, M. F. & Gloster, T. M., 27 Oct 2023, In: Nucleic Acids Research. 51, 19, p. 10590-10605 16 p.

  Research output: Contribution to journal › Article › peer-review

• Open access

  Bioinformatic analysis of type III CRISPR systems reveals key properties and new effector families

  Hoikkala, V. P., Graham, S. & White, M., 8 Jul 2024, In: Nucleic Acids Research. 52, 12, p. 7129–7141 13 p.

  Research output: Contribution to journal › Article › peer-review

• Open access

  Multi-layered genome defences in bacteria

  Agapov, A., Baker, K. S., Bedekar, P., Bhatia, R. P., Blower, T. R., Brockhurst, M. A., Brown, C., Chong, C. E., Fothergill, J. L., Graham, S., Hall, J. P., Maestri, A., McQuarrie, S., Olina, A., Pagliara, S., Recker, M., Richmond, A., Shaw, S. J., Szczelkun, M. D. & Taylor, T. B. & 5 others, van Houte, S., Went, S. C., Westra, E. R., White, M. F. & Wright, R., 1 Apr 2024, In: Current Opinion in Microbiology. 78, 10 p., 102436.

  Research output: Contribution to journal › Review article › peer-review

• Open access

  Reversible conjugation of a CBASS nucleotide cyclase regulates bacterial immune response to phage infection

  Kruger, L., Gaskell-Mew, L., Graham, S., Shirran, S. L., Hertel, R. & White, M., 8 Apr 2024, In: Nature Microbiology. 33 p.

  Research output: Contribution to journal › Article › peer-review

• Open access

  Activation of Csm6 ribonuclease by cyclic nucleotide binding: in an emergency, twist to open

  McQuarrie, S., Athukoralage, J. S., McMahon, S. A., Graham, S., Ackermann, K., Bode, B. E., White, M. F. & Gloster, T. M., 27 Oct 2023, In: Nucleic Acids Research. 51, 19, p. 10590-10605 16 p.

  Research output: Contribution to journal › Article › peer-review

• Open access

  Antiviral type III CRISPR signalling via conjugation of ATP and SAM

  Chi, H., Hoikkala, V. P., Gruschow, S., Graham, S., Shirran, S. L. & White, M., 26 Oct 2023, In: Nature. 622, 7984, p. 826-833 22 p.

  Research output: Contribution to journal › Article › peer-review

• Open access

  Author Correction: Cyclic nucleotide-induced helical structure activates a TIR immune effector (Nature, (2022), 608, 7924, (808-812), 10.1038/s41586-022-05070-9)

  Hogrel, G., Guild, A., Graham, S., Rickman, H., Grüschow, S., Bertrand, Q., Spagnolo, L. & White, M. F., 2 Feb 2023, In: Nature. 614, 7946, p. E15

  Research output: Contribution to journal › Comment/debate › peer-review

• Open access

  Structure of the Saccharolobus solfataricus type III-D CRISPR effector

  Cannone, G., Kompaniiets, D., Graham, S., White, M. & Spagnolo, L., 20 Feb 2023, In: Current Research in Structural Biology. 5, 8 p., 100098.

  Research output: Contribution to journal › Article › peer-review

• Open access

  Structure and mechanism of the type I-G CRISPR effector

  Shangguan, Q., Graham, S., Sundaramoorthy, R. & White, M. F., 28 Oct 2022, In: Nucleic Acids Research. 50, 19, p. 11214-11228 15 p.

  Research output: Contribution to journal › Article › peer-review

• Open access

  The CRISPR ancillary effector Can2 is a dual-specificity nuclease potentiating type III CRISPR defence

  Zhu, W., McQuarrie, S. J., Gruschow, S., McMahon, S., Graham, S., Gloster, T. & White, M., 18 Mar 2021, In: Nucleic Acids Research. 49, 5, p. 2777–2789 13 p., gkab073.

  Research output: Contribution to journal › Article › peer-review

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